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Enzymatic independent role of sphingosine kinase 2 in regulating the expression of type I interferon during influenza A virus infection

Influenza virus has the ability to circumvent host innate immune system through regulating certain host factors for its effective propagation. However, the detailed mechanism is still not fully understood. Here, we report that a host sphingolipid metabolism-related factor, sphingosine kinase 2 (SPHK...

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Detalles Bibliográficos
Autores principales: Xu, Mengqiong, Xia, Sisi, Wang, Mei, Liu, Xiaolian, Li, Xin, Chen, Weijie, Wang, Yaohao, Li, Hongjian, Xia, Chuan, Chen, Jun, Wu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451060/
https://www.ncbi.nlm.nih.gov/pubmed/36070294
http://dx.doi.org/10.1371/journal.ppat.1010794