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Archetypal Analysis for population genetics

The estimation of genetic clusters using genomic data has application from genome-wide association studies (GWAS) to demographic history to polygenic risk scores (PRS) and is expected to play an important role in the analyses of increasingly diverse, large-scale cohorts. However, existing methods ar...

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Detalles Bibliográficos
Autores principales: Gimbernat-Mayol, Julia, Dominguez Mantes, Albert, Bustamante, Carlos D., Mas Montserrat, Daniel, Ioannidis, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451066/
https://www.ncbi.nlm.nih.gov/pubmed/36007005
http://dx.doi.org/10.1371/journal.pcbi.1010301