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SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export

SARS-CoV-2 is a betacoronavirus and the etiological agent of COVID-19, a devastating infectious disease. Due to its far-reaching effect on human health, there is an urgent and growing need to understand the viral molecular biology of SARS-CoV-2 and its interaction with the host cell. SARS-CoV-2 enco...

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Detalles Bibliográficos
Autores principales: Hall, Ross, Guedán, Anabel, Yap, Melvyn W., Young, George R., Harvey, Ruth, Stoye, Jonathan P., Bishop, Kate N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451085/
https://www.ncbi.nlm.nih.gov/pubmed/36007063
http://dx.doi.org/10.1371/journal.ppat.1010349