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Neoantigen‐based cancer vaccination using chimeric RNA‐loaded dendritic cell‐derived extracellular vesicles

Cancer vaccines critically rely on the availability of targetable immunogenic cancer‐specific neoepitopes. However, mutation‐based immunogenic neoantigens are rare or even non‐existent in subgroups of cancer types. To address this issue, we exploited a cancer‐specific aberrant transcription‐induced...

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Detalles Bibliográficos
Autores principales: Xiong, Xiao, Ke, Xiurong, Wang, Lu, Lin, Yusheng, Wang, Shuhong, Yao, Zhimeng, Li, Kai, Luo, Yichen, Liu, Fan, Pan, Yunlong, Yeung, Sai‐Ching J., Helfrich, Wijnand, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451527/
https://www.ncbi.nlm.nih.gov/pubmed/35927827
http://dx.doi.org/10.1002/jev2.12243