Dendritic cell Piezo1 directs the differentiation of T(H)1 and T(reg) cells in cancer

Dendritic cells (DCs) play an important role in anti-tumor immunity by inducing T cell differentiation. Herein, we found that the DC mechanical sensor Piezo1 stimulated by mechanical stiffness or inflammatory signals directs the reciprocal differentiation of T(H)1 and regulatory T (T(reg)) cells in...

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Detalles Bibliográficos
Autores principales: Wang, Yuexin, Yang, Hui, Jia, Anna, Wang, Yufei, Yang, Qiuli, Dong, Yingjie, Hou, Yueru, Cao, Yejin, Dong, Lin, Bi, Yujing, Liu, Guangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451538/
https://www.ncbi.nlm.nih.gov/pubmed/35993548
http://dx.doi.org/10.7554/eLife.79957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451538/
https://www.ncbi.nlm.nih.gov/pubmed/35993548
http://dx.doi.org/10.7554/eLife.79957

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