Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLCγ1 axis

Pulmonary hypertension is a lethal disease characterized by pulmonary vascular remodeling and is mediated by abnormal proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs). Platelet-derived growth factor BB (PDGF-BB) is the most potent mitogen for PASMCs and is involved in v...

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Detalles Bibliográficos
Autores principales: Xu, Junhua, Zhong, Yanfeng, Yin, Haoyang, Linneman, John, Luo, Yixuan, Xia, Sijian, Xia, Qinyi, Yang, Lei, Huang, Xingtao, Kang, Kang, Wang, Jun, Niu, Yanqin, Li, Li, Gou, Deming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451921/
https://www.ncbi.nlm.nih.gov/pubmed/35848503
http://dx.doi.org/10.1097/HJH.0000000000003220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451921/
https://www.ncbi.nlm.nih.gov/pubmed/35848503
http://dx.doi.org/10.1097/HJH.0000000000003220

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