Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL

Recently, chimeric antigen receptor (CAR)-T cell therapy has shown great promise in treating haematological malignancies(1–7). However, CAR-T cell therapy currently has several limitations(8–12). Here we successfully developed a two-in-one approach to generate non-viral, gene-specific targeted CAR-T...

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Detalles Bibliográficos
Autores principales: Zhang, Jiqin, Hu, Yongxian, Yang, Jiaxuan, Li, Wei, Zhang, Mingming, Wang, Qingcan, Zhang, Linjie, Wei, Guoqing, Tian, Yue, Zhao, Kui, Chen, Ang, Tan, Binghe, Cui, Jiazhen, Li, Deqi, Li, Yi, Qi, Yalei, Wang, Dongrui, Wu, Yuxuan, Li, Dali, Du, Bing, Liu, Mingyao, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452296/
https://www.ncbi.nlm.nih.gov/pubmed/36045296
http://dx.doi.org/10.1038/s41586-022-05140-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452296/
https://www.ncbi.nlm.nih.gov/pubmed/36045296
http://dx.doi.org/10.1038/s41586-022-05140-y

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