A microbial supply chain for production of the anti-cancer drug vinblastine

Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary metabolites with many medicinal properties, including the essential anti-cancer therapeutics vinblastine and vincristine(1). As MIAs are difficult to chemically synthesize, the world’s supply chain for vinblastine re...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Hansen, Lea G., Gudich, Olga, Viehrig, Konrad, Lassen, Lærke M. M., Schrübbers, Lars, Adhikari, Khem B., Rubaszka, Paulina, Carrasquer-Alvarez, Elena, Chen, Ling, D’Ambrosio, Vasil, Lehka, Beata, Haidar, Ahmad K., Nallapareddy, Saranya, Giannakou, Konstantina, Laloux, Marcos, Arsovska, Dushica, Jørgensen, Marcus A. K., Chan, Leanne Jade G., Kristensen, Mette, Christensen, Hanne B., Sudarsan, Suresh, Stander, Emily A., Baidoo, Edward, Petzold, Christopher J., Wulff, Tune, O’Connor, Sarah E., Courdavault, Vincent, Jensen, Michael K., Keasling, Jay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452304/
https://www.ncbi.nlm.nih.gov/pubmed/36045295
http://dx.doi.org/10.1038/s41586-022-05157-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452304/
https://www.ncbi.nlm.nih.gov/pubmed/36045295
http://dx.doi.org/10.1038/s41586-022-05157-3

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