Scalable, Chemoselective Nickel Electrocatalytic Sulfinylation of Aryl Halides with SO(2)

Simple access to aryl sulfinates from aryl iodides and bromides is reported using an inexpensive Ni‐electrocatalytic protocol. The reaction exhibits a broad scope, uses stock solution of simple SO(2) as sulfur source, and can be scaled up in batch and recycle flow settings. The limitations of this r...

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Detalles Bibliográficos
Autores principales: Lou, Terry Shing‐Bong, Kawamata, Yu, Ewing, Tamara, Correa‐Otero, Guillermo A., Collins, Michael R., Baran, Phil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452475/
https://www.ncbi.nlm.nih.gov/pubmed/35819400
http://dx.doi.org/10.1002/anie.202208080
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author Lou, Terry Shing‐Bong
Kawamata, Yu
Ewing, Tamara
Correa‐Otero, Guillermo A.
Collins, Michael R.
Baran, Phil S.
author_facet Lou, Terry Shing‐Bong
Kawamata, Yu
Ewing, Tamara
Correa‐Otero, Guillermo A.
Collins, Michael R.
Baran, Phil S.
author_sort Lou, Terry Shing‐Bong
collection PubMed
description Simple access to aryl sulfinates from aryl iodides and bromides is reported using an inexpensive Ni‐electrocatalytic protocol. The reaction exhibits a broad scope, uses stock solution of simple SO(2) as sulfur source, and can be scaled up in batch and recycle flow settings. The limitations of this reaction are clearly shown and put into context by benchmarking with state‐of‐the‐art Pd‐based methods.
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spelling pubmed-94524752022-10-14 Scalable, Chemoselective Nickel Electrocatalytic Sulfinylation of Aryl Halides with SO(2) Lou, Terry Shing‐Bong Kawamata, Yu Ewing, Tamara Correa‐Otero, Guillermo A. Collins, Michael R. Baran, Phil S. Angew Chem Int Ed Engl Research Articles Simple access to aryl sulfinates from aryl iodides and bromides is reported using an inexpensive Ni‐electrocatalytic protocol. The reaction exhibits a broad scope, uses stock solution of simple SO(2) as sulfur source, and can be scaled up in batch and recycle flow settings. The limitations of this reaction are clearly shown and put into context by benchmarking with state‐of‐the‐art Pd‐based methods. John Wiley and Sons Inc. 2022-08-03 2022-09-12 /pmc/articles/PMC9452475/ /pubmed/35819400 http://dx.doi.org/10.1002/anie.202208080 Text en © 2022 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Lou, Terry Shing‐Bong
Kawamata, Yu
Ewing, Tamara
Correa‐Otero, Guillermo A.
Collins, Michael R.
Baran, Phil S.
Scalable, Chemoselective Nickel Electrocatalytic Sulfinylation of Aryl Halides with SO(2)
title Scalable, Chemoselective Nickel Electrocatalytic Sulfinylation of Aryl Halides with SO(2)
title_full Scalable, Chemoselective Nickel Electrocatalytic Sulfinylation of Aryl Halides with SO(2)
title_fullStr Scalable, Chemoselective Nickel Electrocatalytic Sulfinylation of Aryl Halides with SO(2)
title_full_unstemmed Scalable, Chemoselective Nickel Electrocatalytic Sulfinylation of Aryl Halides with SO(2)
title_short Scalable, Chemoselective Nickel Electrocatalytic Sulfinylation of Aryl Halides with SO(2)
title_sort scalable, chemoselective nickel electrocatalytic sulfinylation of aryl halides with so(2)
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452475/
https://www.ncbi.nlm.nih.gov/pubmed/35819400
http://dx.doi.org/10.1002/anie.202208080
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