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Distinguishing post‐translational modifications in dominantly inherited frontotemporal dementias: FTLD‐TDP Type A (GRN) vs Type B (C9orf72)

AIMS: Frontotemporal dementias are neuropathologically characterised by frontotemporal lobar degeneration (FTLD). Intraneuronal inclusions of transactive response DNA‐binding protein 43 kDa (TDP‐43) are the defining pathological hallmark of approximately half of the FTLD cases, being referred to as...

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Detalles Bibliográficos
Autores principales: Cracco, Laura, Doud, Emma H., Hallinan, Grace I., Garringer, Holly J., Jacobsen, Max H., Richardson, Rose M., Buratti, Emanuele, Vidal, Ruben, Ghetti, Bernardino, Newell, Kathy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452479/
https://www.ncbi.nlm.nih.gov/pubmed/35836354
http://dx.doi.org/10.1111/nan.12836