Coiled-coil structure of meiosis protein TEX12 and conformational regulation by its C-terminal tip

Meiosis protein TEX12 is an essential component of the synaptonemal complex (SC), which mediates homologous chromosome synapsis. It is also recruited to centrosomes in meiosis, and aberrantly in certain cancers, leading to centrosome dysfunction. Within the SC, TEX12 forms an intertwined complex wit...

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Detalles Bibliográficos
Autores principales: Dunce, James M., Salmon, Lucy J., Davies, Owen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452514/
https://www.ncbi.nlm.nih.gov/pubmed/36071143
http://dx.doi.org/10.1038/s42003-022-03886-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452514/
https://www.ncbi.nlm.nih.gov/pubmed/36071143
http://dx.doi.org/10.1038/s42003-022-03886-9

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