Regulating Nrf2-GPx4 axis by bicyclol can prevent ferroptosis in carbon tetrachloride-induced acute liver injury in mice

Hepatocellular death is a sensitive parameter for detecting acute liver injury (ALI) of toxic, viral, metabolic, and autoimmune origin. Ferroptosis has recently been implicated in carbon tetrachloride (CCl(4))-induced ALI. However, the underpinning mechanism and mechanistic basis remain elusive. In...

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Detalles Bibliográficos
Autores principales: Zhao, Tianming, Yu, Zihan, Zhou, Lei, Wang, Xiaoyu, Hui, Yangyang, Mao, Lihong, Fan, Xiaofei, Wang, Bangmao, Zhao, Xingliang, Sun, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452542/
https://www.ncbi.nlm.nih.gov/pubmed/36071041
http://dx.doi.org/10.1038/s41420-022-01173-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452542/
https://www.ncbi.nlm.nih.gov/pubmed/36071041
http://dx.doi.org/10.1038/s41420-022-01173-4

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