A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation

Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer, and resistant to both conventional and targeted chemotherapy. Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to decrease the incidence and mortality of different types of cancers. Here, we investigated the cell...

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Detalles Bibliográficos
Autores principales: Kahraman, Deniz Cansen, Bilget Guven, Ebru, Aytac, Peri S., Aykut, Gamze, Tozkoparan, Birsen, Cetin Atalay, Rengul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452548/
https://www.ncbi.nlm.nih.gov/pubmed/36071119
http://dx.doi.org/10.1038/s41598-022-17444-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452548/
https://www.ncbi.nlm.nih.gov/pubmed/36071119
http://dx.doi.org/10.1038/s41598-022-17444-0

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