Uncoupling of Voltage- and Ligand-Induced Activation in HCN2 Channels by Glycine Inserts

Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels are tetramers that generate electrical rhythmicity in special brain neurons and cardiomyocytes. The channels are activated by membrane hyperpolarization. The binding of cAMP to the four available cyclic nucleotide-binding domains...

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Detalles Bibliográficos
Autores principales: Yüksel, Sezin, Bonus, Michele, Schwabe, Tina, Pfleger, Christopher, Zimmer, Thomas, Enke, Uta, Saß, Inga, Gohlke, Holger, Benndorf, Klaus, Kusch, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452628/
https://www.ncbi.nlm.nih.gov/pubmed/36091400
http://dx.doi.org/10.3389/fphys.2022.895324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452628/
https://www.ncbi.nlm.nih.gov/pubmed/36091400
http://dx.doi.org/10.3389/fphys.2022.895324

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