LINC-PINT suppresses cisplatin resistance in gastric cancer by inhibiting autophagy activation via epigenetic silencing of ATG5 by EZH2

Resistance to cisplatin (DDP) is a major obstacle in the clinical treatment of advanced gastric cancer (GC). Long noncoding RNA (lncRNA) play a significant regulatory role in the development and drug resistance of GC. In this study, we reported that the lncRNA LINC-PINT was downregulated in DDP-resi...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng, Kang, Tong, Wang, Xinyi, Wang, Jizhao, Liu, Lin, Zhang, Jiawei, Liu, Xu, Li, Rong, Wang, Jiansheng, Zhang, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452659/
https://www.ncbi.nlm.nih.gov/pubmed/36091809
http://dx.doi.org/10.3389/fphar.2022.968223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452659/
https://www.ncbi.nlm.nih.gov/pubmed/36091809
http://dx.doi.org/10.3389/fphar.2022.968223

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