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NFYA promotes the anti-tumor effects of gluconeogenesis in hepatocellular carcinoma through the regulation of PCK1 expression

Reprogramming of glucose metabolism occurs in many human tumor types, and one of these, gluconeogenesis, is known to exhibit anti-tumor effects in hepatocellular carcinoma (HCC). The transcription factor NFYA regulates gluconeogenesis in the normal liver tissue, but the function of the NFYA-gluconeo...

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Detalles Bibliográficos
Autores principales: Tsujimoto, Goki, Ito, Rin, Yoshikawa, Kei, Ueki, Chihiro, Okada, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452718/
https://www.ncbi.nlm.nih.gov/pubmed/36092708
http://dx.doi.org/10.3389/fcell.2022.983599