Cargando…

NFYA promotes the anti-tumor effects of gluconeogenesis in hepatocellular carcinoma through the regulation of PCK1 expression

Reprogramming of glucose metabolism occurs in many human tumor types, and one of these, gluconeogenesis, is known to exhibit anti-tumor effects in hepatocellular carcinoma (HCC). The transcription factor NFYA regulates gluconeogenesis in the normal liver tissue, but the function of the NFYA-gluconeo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsujimoto, Goki, Ito, Rin, Yoshikawa, Kei, Ueki, Chihiro, Okada, Nobuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452718/ https://www.ncbi.nlm.nih.gov/pubmed/36092708 http://dx.doi.org/10.3389/fcell.2022.983599

Ejemplares similares

NFYA promotes malignant behavior of triple-negative breast cancer in mice through the regulation of lipid metabolism
por: Okada, Nobuhiro, et al.
Publicado: (2023)

SHP-1 phosphatase acts as a coactivator of PCK1 transcription to control gluconeogenesis
por: Kumar, Amit, et al.
Publicado: (2023)

Hepatic retinaldehyde deficiency is involved in diabetes deterioration by enhancing PCK1- and G6PC-mediated gluconeogenesis
por: Yang, Hanyu, et al.
Publicado: (2023)

6-Phosphogluconolactonase Promotes Hepatocellular Carcinogenesis by Activating Pentose Phosphate Pathway
por: Li, Changzheng, et al.
Publicado: (2021)

Possible Therapeutic Utility of anti-Cell Adhesion Molecule 1 Antibodies for Malignant Pleural Mesothelioma
por: Hagiyama, Man, et al.
Publicado: (2022)

RPL19 Is a Prognostic Biomarker and Promotes Tumor Progression in Hepatocellular Carcinoma
por: Rao, Benchen, et al.
Publicado: (2021)

Anti-tumor Effect of Oleic Acid in Hepatocellular Carcinoma Cell Lines via Autophagy Reduction
por: Giulitti, Federico, et al.
Publicado: (2021)

BAP31 Promotes Tumor Cell Proliferation by Stabilizing SERPINE2 in Hepatocellular Carcinoma
por: Zhang, Xiyang, et al.
Publicado: (2020)

REG4 promotes the proliferation and anti-apoptosis of cancer
por: Zheng, Hua-Chuan, et al.
Publicado: (2022)

Commentary: Anti-tumor Effect of Oleic Acid in Hepatocellular Carcinoma Cell Lines via Autophagy Reduction
por: Lin, Jiong
Publicado: (2021)

Glycogen Phosphorylase B Is Regulated by miR101-3p and Promotes Hepatocellular Carcinoma Tumorigenesis
por: Cui, Guangying, et al.
Publicado: (2020)

GINS1 Induced Sorafenib Resistance by Promoting Cancer Stem Properties in Human Hepatocellular Cancer Cells
por: Li, Sheng, et al.
Publicado: (2021)

Integrated Analysis Reveals the Gut Microbial Metabolite TMAO Promotes Inflammatory Hepatocellular Carcinoma by Upregulating POSTN
por: Wu, Yonglin, et al.
Publicado: (2022)

Promoter Hypomethylation and miR-145-5p Downregulation- Mediated HDAC11 Overexpression Promotes Sorafenib Resistance and Metastasis of Hepatocellular Carcinoma Cells
por: Wang, Wenlong, et al.
Publicado: (2020)

Cleavage and Polyadenylation Specific Factor 1 Promotes Tumor Progression via Alternative Polyadenylation and Splicing in Hepatocellular Carcinoma
por: Chen, Shi-lu, et al.
Publicado: (2021)

Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α
por: Wang, Meng, et al.
Publicado: (2021)

ARPC2: A Pan-Cancer Prognostic and Immunological Biomarker That Promotes Hepatocellular Carcinoma Cell Proliferation and Invasion
por: Huang, Shenglan, et al.
Publicado: (2022)

Cancer-Associated Fibroblasts Promote Vascular Invasion of Hepatocellular Carcinoma via Downregulating Decorin-integrin β1 Signaling
por: Zheng, Xiaobo, et al.
Publicado: (2021)

LncRNA CRNDE Promotes ATG4B-Mediated Autophagy and Alleviates the Sensitivity of Sorafenib in Hepatocellular Carcinoma Cells
por: Chen, Lingxi, et al.
Publicado: (2021)

ORC6, Negatively Regulated by miR-1-3p, Promotes Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells
por: Chen, Hu, et al.
Publicado: (2021)

Sulfatase 2-Induced Cancer-Associated Fibroblasts Promote Hepatocellular Carcinoma Progression via Inhibition of Apoptosis and Induction of Epithelial-to-Mesenchymal Transition
por: Wang, Cong, et al.
Publicado: (2021)

Long Noncoding RNA LINC01134 Promotes Hepatocellular Carcinoma Metastasis via Activating AKT1S1 and NF-κB Signaling
por: Wang, Chao, et al.
Publicado: (2020)

M(6)A-Mediated Upregulation of LINC00106 Promotes Stemness and Metastasis Properties of Hepatocellular Carcinoma via Sponging Let7f
por: Liang, Wenjin, et al.
Publicado: (2021)

CircUBAP2 Promotes MMP9-Mediated Oncogenic Effect via Sponging miR-194-3p in Hepatocellular Carcinoma
por: Liu, Boqiang, et al.
Publicado: (2021)

NAP1L1 Functions as a Tumor Promoter via Recruiting Hepatoma-Derived Growth Factor/c-Jun Signal in Hepatocellular Carcinoma
por: Zhang, Ye-wei, et al.
Publicado: (2021)

CircCRIM1 Promotes Hepatocellular Carcinoma Proliferation and Angiogenesis by Sponging miR-378a-3p and Regulating SKP2 Expression
por: Ji, Yang, et al.
Publicado: (2021)

The Critical Role of Ferroptosis in Hepatocellular Carcinoma
por: Pan, Fan, et al.
Publicado: (2022)

Significance of Liver Zonation in Hepatocellular Carcinoma
por: Yu, Shizhe, et al.
Publicado: (2022)

Icariin-loaded hydrogel with concurrent chondrogenesis and anti-inflammatory properties for promoting cartilage regeneration in a large animal model
por: Xu, Songshan, et al.
Publicado: (2022)

The Function of the HGF/c-Met Axis in Hepatocellular Carcinoma
por: Wang, Haiyu, et al.
Publicado: (2020)

Probing Synergistic Targets by Natural Compounds for Hepatocellular Carcinoma
por: Gao, Jian, et al.
Publicado: (2021)

The Role of Ferroptosis in the Treatment and Drug Resistance of Hepatocellular Carcinoma
por: Zhao, Siqi, et al.
Publicado: (2022)

Novel Insights in the Regulatory Mechanisms of Ferroptosis in Hepatocellular Carcinoma
por: Ma, Shiwen, et al.
Publicado: (2022)

Immunometabolic factors contributing to obesity-linked hepatocellular carcinoma
por: Akl, May G., et al.
Publicado: (2023)

Targeting PIN1 as a Therapeutic Approach for Hepatocellular Carcinoma
por: Cheng, Chi-Wai, et al.
Publicado: (2020)

CLEC4s as Potential Therapeutic Targets in Hepatocellular Carcinoma Microenvironment
por: Zhang, Yinjiang, et al.
Publicado: (2021)

A Novel Pyroptosis-related Prognostic Model for Hepatocellular Carcinoma
por: Wu, Qianqian, et al.
Publicado: (2021)

Cholesterol Metabolism: A Double-Edged Sword in Hepatocellular Carcinoma
por: Zhou, Fangli, et al.
Publicado: (2021)

Machine learning identifies exosome features related to hepatocellular carcinoma
por: Zhu, Kai, et al.
Publicado: (2022)

PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis
por: Yamaguchi, Norihiro, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_le0j7qkb0rj74u4pdtinc9h0ri