Identification of amino acid residues in the MT-loop of MT1-MMP critical for its ability to cleave low-density lipoprotein receptor

Low-density lipoprotein receptor (LDLR) mediates clearance of plasma LDL cholesterol, preventing the development of atherosclerosis. We previously demonstrated that membrane type 1-matrix metalloproteinase (MT1-MMP) cleaves LDLR and exacerbates the development of atherosclerosis. Here, we investigat...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Maggie, Alabi, Adekunle, Gu, Hong-mei, Gill, Govind, Zhang, Ziyang, Jarad, Suha, Xia, Xiao-dan, Shen, Yishi, Wang, Gui-qing, Zhang, Da-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452735/
https://www.ncbi.nlm.nih.gov/pubmed/36093157
http://dx.doi.org/10.3389/fcvm.2022.917238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452735/
https://www.ncbi.nlm.nih.gov/pubmed/36093157
http://dx.doi.org/10.3389/fcvm.2022.917238

Ejemplares similares