The Smad3-dependent microRNA let-7i-5p promoted renal fibrosis in mice with unilateral ureteral obstruction

Renal fibrosis is a common feature of all types of chronic kidney disease (CKD) and is tightly regulated by the TGF-β/Smad3 pathway. Let-7i-5p belongs to the let-7 microRNA family with diverse biological functions. It has been reported that let-7i-5p suppresses fibrotic disease in the heart, lungs,...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Ze, Guo, Huai-Ying, Li, Yu-Qing, Li, Jian-Chun, Yang, Xiao-Hong, Liu, Jian, Hu, Qiong-Dan, Wang, Hong-Lian, Wang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452756/
https://www.ncbi.nlm.nih.gov/pubmed/36091385
http://dx.doi.org/10.3389/fphys.2022.937878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452756/
https://www.ncbi.nlm.nih.gov/pubmed/36091385
http://dx.doi.org/10.3389/fphys.2022.937878

Ejemplares similares