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The Smad3-dependent microRNA let-7i-5p promoted renal fibrosis in mice with unilateral ureteral obstruction

Renal fibrosis is a common feature of all types of chronic kidney disease (CKD) and is tightly regulated by the TGF-β/Smad3 pathway. Let-7i-5p belongs to the let-7 microRNA family with diverse biological functions. It has been reported that let-7i-5p suppresses fibrotic disease in the heart, lungs,...

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Detalles Bibliográficos
Autores principales:	Peng, Ze, Guo, Huai-Ying, Li, Yu-Qing, Li, Jian-Chun, Yang, Xiao-Hong, Liu, Jian, Hu, Qiong-Dan, Wang, Hong-Lian, Wang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452756/ https://www.ncbi.nlm.nih.gov/pubmed/36091385 http://dx.doi.org/10.3389/fphys.2022.937878

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