NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy

A ferritin particle consists of 24 ferritin proteins (FTH1 and FTL) and stores iron ions within it. During iron deficiency, ferritin particles are transported to lysosomes to release iron ions. Two transport pathways have been reported: macroautophagy and ESCRT-dependent endosomal microautophagy. Al...

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Detalles Bibliográficos
Autores principales: Ohshima, Tomoko, Yamamoto, Hayashi, Sakamaki, Yuriko, Saito, Chieko, Mizushima, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452830/
https://www.ncbi.nlm.nih.gov/pubmed/36066504
http://dx.doi.org/10.1083/jcb.202203102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452830/
https://www.ncbi.nlm.nih.gov/pubmed/36066504
http://dx.doi.org/10.1083/jcb.202203102

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