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Influenza virus causes lung immunopathology through down-regulating PPARγ activity in macrophages

Fatal influenza (flu) virus infection often activates excessive inflammatory signals, leading to multi-organ failure and death, also referred to as cytokine storm. PPARγ (Peroxisome proliferator-activated receptor gamma) agonists are well-known candidates for cytokine storm modulation. The present s...

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Detalles Bibliográficos
Autores principales: Zhang, Hongbo, Alford, Taylor, Liu, Shuangquan, Zhou, Dongming, Wang, Jieru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452838/
https://www.ncbi.nlm.nih.gov/pubmed/36091002
http://dx.doi.org/10.3389/fimmu.2022.958801