Systematic evaluation for the causal effects of blood metabolites on osteoporosis: Genetic risk score and Mendelian randomization

PURPOSE: Osteoporosis is associated with metabolic alterations, but the causal roles of serum metabolites on osteoporosis have not been identified. METHODS: Based on the large individual-level datasets from UK Biobank as well as GWAS summary datasets, we first constructed genetic risk scores (GRSs)...

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Detalles Bibliográficos
Autores principales: Yu, Xing-Hao, Cao, Rong-Rong, Yang, Yi-Qun, Zhang, Lei, Lei, Shu-Feng, Deng, Fei-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452842/
https://www.ncbi.nlm.nih.gov/pubmed/36091497
http://dx.doi.org/10.3389/fpubh.2022.905178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452842/
https://www.ncbi.nlm.nih.gov/pubmed/36091497
http://dx.doi.org/10.3389/fpubh.2022.905178

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