The female syndecan-4(−/−) heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels

Background: In cardiac muscle, the ubiquitously expressed proteoglycan syndecan-4 is involved in the hypertrophic response to pressure overload. Protein kinase Akt signaling, which is known to regulate hypertrophy, has been found to be reduced in the cardiac muscle of exercised male syndecan-4(−/−)...

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Detalles Bibliográficos
Autores principales: Støle, Thea Parsberg, Lunde, Marianne, Shen, Xin, Martinsen, Marita, Lunde, Per Kristian, Li, Jia, Lockwood, Francesca, Sjaastad, Ivar, Louch, William Edward, Aronsen, Jan Magnus, Christensen, Geir, Carlson, Cathrine Rein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452846/
https://www.ncbi.nlm.nih.gov/pubmed/36092718
http://dx.doi.org/10.3389/fcell.2022.908126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452846/
https://www.ncbi.nlm.nih.gov/pubmed/36092718
http://dx.doi.org/10.3389/fcell.2022.908126

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