Pharmacoinformatic study of inhibitory potentials of selected flavonoids against papain-like protease and 3-chymotrypsin-like protease of SARS-CoV-2

BACKGROUND: Inhibition of papain-like protease (PLpro) and 3-chymotrypsin-like protease (3CLpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is projected to terminate its replication. Hence, these proteases represent viable therapeutic targets. METHODS: Sixty-one flavonoids with...

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Detalles Bibliográficos
Autores principales: Tijjani, Habibu, Adegunloye, Adegbenro P., Uba, Auwalu, Adebayo, Joseph O., Gyebi, Gideon A., Ibrahim, Ibrahim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452863/
http://dx.doi.org/10.1186/s40816-022-00347-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452863/
http://dx.doi.org/10.1186/s40816-022-00347-y

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