Drug affinity-responsive target stability unveils filamins as biological targets for artemetin, an anti-cancer flavonoid

Artemetin is a valuable 5-hydroxy-3,6,7,3′,4′-pentamethoxyflavone present in many different medicinal plants with very good oral bioavailability and drug-likeness values, owing to numerous bioactivities, such as anti-inflammatory and anti-cancer ones. Here, a multi-disciplinary plan has been settled...

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Detalles Bibliográficos
Autores principales: Ferraro, Giusy, Belvedere, Raffaella, Petrella, Antonello, Tosco, Alessandra, Stork, Björn, Salamone, Stefano, Minassi, Alberto, Pollastro, Federica, Morretta, Elva, Monti, Maria Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452882/
https://www.ncbi.nlm.nih.gov/pubmed/36090055
http://dx.doi.org/10.3389/fmolb.2022.964295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452882/
https://www.ncbi.nlm.nih.gov/pubmed/36090055
http://dx.doi.org/10.3389/fmolb.2022.964295

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