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OcclusionChip: A functional microcapillary occlusion assay complementary to ektacytometry for detection of small-fraction red blood cells with abnormal deformability

Red blood cell (RBC) deformability is a valuable hemorheological biomarker that can be used to assess the clinical status and response to therapy of individuals with sickle cell disease (SCD). RBC deformability has been measured by ektacytometry for decades, which uses shear or osmolar stress. Howev...

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Detalles Bibliográficos
Autores principales: Man, Yuncheng, An, Ran, Monchamp, Karamoja, Sekyonda, Zoe, Kucukal, Erdem, Federici, Chiara, Wulftange, William J., Goreke, Utku, Bode, Allison, Sheehan, Vivien A., Gurkan, Umut A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452903/
https://www.ncbi.nlm.nih.gov/pubmed/36091387
http://dx.doi.org/10.3389/fphys.2022.954106