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Protein of a thousand faces: The tumor-suppressive and oncogenic responses of p53
The p53 protein is a pleiotropic regulator working as a tumor suppressor and as an oncogene. Depending on the cellular insult and the mutational status, p53 may trigger opposing activities such as cell death or survival, senescence and cell cycle arrest or proliferative signals, antioxidant or proox...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452956/ https://www.ncbi.nlm.nih.gov/pubmed/36090037 http://dx.doi.org/10.3389/fmolb.2022.944955 |