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ADAM33 Silencing Inhibits Vascular Smooth Muscle Cell Migration and Regulates Cytokine Secretion in Airway Vascular Remodeling via the PI3K/AKT/mTOR Pathway

INTRODUCTION: Vascular smooth muscle cells (VSMCs) are highly involved in airway vascular remodeling in asthma. OBJECTIVES: This study aimed to investigate the mechanisms underlying the effects of a disintegrin and metalloproteinase-33 (ADAM33) gene on the migration capacity and inflammatory cytokin...

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Detalles Bibliográficos
Autores principales: Yan, Fang, Hu, Xin, He, Long, Jiao, Kegang, Hao, Yanyan, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453083/
https://www.ncbi.nlm.nih.gov/pubmed/36091328
http://dx.doi.org/10.1155/2022/8437348