New, potent, small molecule agonists of tyrosine kinase receptors attenuate dry eye disease

Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin3 (NT-3) bind to tyrosine kinase (Trk) receptors, TrkA, TrkB, and TrkC, respectively. This study investigated the efficacy of novel molecule agonists of Trk receptors in an in vivo model of dry eye disease (DED). Sm...

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Detalles Bibliográficos
Autores principales: Yu, Zhiyuan, Joy, Shaon, Mi, Tianxiong, Yazdanpanah, Ghasem, Burgess, Kevin, de Paiva, Cintia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453230/
https://www.ncbi.nlm.nih.gov/pubmed/36091713
http://dx.doi.org/10.3389/fmed.2022.937142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453230/
https://www.ncbi.nlm.nih.gov/pubmed/36091713
http://dx.doi.org/10.3389/fmed.2022.937142

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