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A newly identified secreted larval antigen elicits basophil-dependent protective immunity against N. brasiliensis infection

Hookworms infect more that 400 million people and cause significant socio-economic burden on endemic countries. The lack of efficient vaccines and the emergence of anthelminthic drug resistance are of major concern. Free-living hookworm larvae infect their hosts via the skin and live as adult worms...

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Detalles Bibliográficos
Autores principales: Thuma, Natalie, Döhler, Daniela, Mielenz, Dirk, Sticht, Heinrich, Radtke, Daniel, Reimann, Lena, Warscheid, Bettina, Voehringer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453252/
https://www.ncbi.nlm.nih.gov/pubmed/36091065
http://dx.doi.org/10.3389/fimmu.2022.979491