A sequentially triggered DNA nanocapsule for targeted drug delivery based on pH-responsive i-motif and tumor cell-specific aptamer

Targeted drug delivery with minor off-target effects is urgently needed for precise cancer treatments. Here, a sequentially triggered strategy based on double targeting elements is designed to meet this purpose. By using an acidic pH-responsive i-motif DNA and a tumor cell-specific aptamer as target...

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Detalles Bibliográficos
Autores principales: Yuan, Baoyin, Xi, Yanan, Qi, Cuihua, Zhao, Mingzhu, Zhu, Xiaoyan, Tang, Jinlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453301/
https://www.ncbi.nlm.nih.gov/pubmed/36091462
http://dx.doi.org/10.3389/fbioe.2022.965337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453301/
https://www.ncbi.nlm.nih.gov/pubmed/36091462
http://dx.doi.org/10.3389/fbioe.2022.965337

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