Design, synthesis, and anticancer activity of three novel palbociclib derivatives

Cancer is one of the most serious diseases threatening human health, so it is particularly important to develop effective tumor-targeting drugs. As the first CDK4/6 inhibitor, palbociclib effectively inhibits tumor proliferation by blocking the cell cycle to the G1 phase. 10-HCPT is a Topo I inhibit...

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Detalles Bibliográficos
Autores principales: Li, Tian, Zhou, An-Di, Bai, Li-Fei, Zhang, Xiao-Yang, Zhou, Yu-Ting, Yang, Hai-Li, Xu, Le-Tian, Guo, Xin-Qin, Zhu, Xi-Yu, Wang, Dong-Jin, Gu, Hong-Wei, Wang, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453454/
https://www.ncbi.nlm.nih.gov/pubmed/36091173
http://dx.doi.org/10.3389/fonc.2022.959322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453454/
https://www.ncbi.nlm.nih.gov/pubmed/36091173
http://dx.doi.org/10.3389/fonc.2022.959322

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