Using Mendelian randomization to explore the gateway hypothesis: possible causal effects of smoking initiation and alcohol consumption on substance use outcomes

BACKGROUND AND AIMS: Initial use of drugs such as tobacco and alcohol may lead to subsequent more problematic drug use—the ‘gateway’ hypothesis. However, observed associations may be due to a shared underlying risk factor, such as trait impulsivity. We used bidirectional Mendelian randomization (MR)...

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Detalles Bibliográficos
Autores principales: Reed, Zoe E., Wootton, Robyn E., Munafò, Marcus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453475/
https://www.ncbi.nlm.nih.gov/pubmed/34590374
http://dx.doi.org/10.1111/add.15673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453475/
https://www.ncbi.nlm.nih.gov/pubmed/34590374
http://dx.doi.org/10.1111/add.15673

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