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Small molecule modulation of the large-conductance calcium-activated potassium channel suppresses salicylate-induced tinnitus in mice

Tinnitus is the phantom perception of sound that has no external source. A neurological signature of tinnitus, and the frequently associated hyperacusis, is an imbalance between excitatory and inhibitory activity in the central auditory system (CAS), leading to dysregulated network excitability. The...

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Detalles Bibliográficos
Autores principales: Scott, Luisa L., Lowe, Andrea S., Brecht, Elliott J., Franco-Waite, Luis, Walton, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453485/
https://www.ncbi.nlm.nih.gov/pubmed/36090293
http://dx.doi.org/10.3389/fnins.2022.763855