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The hedgehog pathway in hematopoiesis and hematological malignancy

The Hedgehog (HH) pathway is a promising therapeutic target in hematological malignancies. Activation of the pathway has been tied to greater chances of relapse and poorer outcomes in several hematological malignancies and inhibiting the pathway has improved outcomes in several clinical trials. One...

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Detalles Bibliográficos
Autores principales: Lemos, Tucker, Merchant, Akil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453489/
https://www.ncbi.nlm.nih.gov/pubmed/36091167
http://dx.doi.org/10.3389/fonc.2022.960943