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The metabolic fate of oxaliplatin in the biological milieu investigated during in vivo lung perfusion using a unique miniaturized sampling approach based on solid-phase microextraction coupled with liquid chromatography-mass spectrometry

Adjuvant chemotherapy after pulmonary metastasectomy for colorectal cancer may reduce recurrence and improve survival rates; however, the benefits of this treatment are limited by the significant side effects that accompany it. The development of a novel in vivo lung perfusion (IVLP) platform would...

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Detalles Bibliográficos
Autores principales: Olkowicz, Mariola, Rosales-Solano, Hernando, Ramadan, Khaled, Wang, Aizhou, Cypel, Marcelo, Pawliszyn, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453651/
https://www.ncbi.nlm.nih.gov/pubmed/36092704
http://dx.doi.org/10.3389/fcell.2022.928152