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The metabolic fate of oxaliplatin in the biological milieu investigated during in vivo lung perfusion using a unique miniaturized sampling approach based on solid-phase microextraction coupled with liquid chromatography-mass spectrometry
Adjuvant chemotherapy after pulmonary metastasectomy for colorectal cancer may reduce recurrence and improve survival rates; however, the benefits of this treatment are limited by the significant side effects that accompany it. The development of a novel in vivo lung perfusion (IVLP) platform would...
Autores principales: | Olkowicz, Mariola, Rosales-Solano, Hernando, Ramadan, Khaled, Wang, Aizhou, Cypel, Marcelo, Pawliszyn, Janusz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453651/ https://www.ncbi.nlm.nih.gov/pubmed/36092704 http://dx.doi.org/10.3389/fcell.2022.928152 |
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