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Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3

Enteroviruses cause a number of medically relevant and widespread human diseases with no approved antiviral therapies currently available. Host-directed therapies present an enticing option for this diverse genus of viruses. We have previously identified the actin histidine methyltransferase SETD3 a...

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Detalles Bibliográficos
Autores principales: Peters, Christine E., Schulze-Gahmen, Ursula, Eckhardt, Manon, Jang, Gwendolyn M., Xu, Jiewei, Pulido, Ernst H., Bardine, Conner, Craik, Charles S., Ott, Melanie, Gozani, Or, Verba, Kliment A., Hüttenhain, Ruth, Carette, Jan E., Krogan, Nevan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453702/
https://www.ncbi.nlm.nih.gov/pubmed/36075902
http://dx.doi.org/10.1038/s41467-022-32758-3