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Function and structure of bradykinin receptor 2 for drug discovery
Type 2 bradykinin receptor (B2R) is an essential G protein-coupled receptor (GPCR) that regulates the cardiovascular system as a vasodepressor. Dysfunction of B2R is also closely related to cancers and hereditary angioedema (HAE). Although several B2R agonists and antagonists have been developed, ic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Nature Singapore
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453710/ https://www.ncbi.nlm.nih.gov/pubmed/36075965 http://dx.doi.org/10.1038/s41401-022-00982-8 |