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Function and structure of bradykinin receptor 2 for drug discovery

Type 2 bradykinin receptor (B2R) is an essential G protein-coupled receptor (GPCR) that regulates the cardiovascular system as a vasodepressor. Dysfunction of B2R is also closely related to cancers and hereditary angioedema (HAE). Although several B2R agonists and antagonists have been developed, ic...

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Detalles Bibliográficos
Autores principales: Shen, Jin-kang, Zhang, Hai-tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453710/
https://www.ncbi.nlm.nih.gov/pubmed/36075965
http://dx.doi.org/10.1038/s41401-022-00982-8