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Validation of an FFF-MALS Method to Characterize the Production and Functionalization of Outer-Membrane Vesicles for Conjugate Vaccines

[Image: see text] With the ongoing development of conjugate vaccines battling infectious diseases, there is a need for novel carriers. Although tetanus toxoid and CRM197 belong to the traditional carrier proteins, outer-membrane vesicles (OMVs) are an excellent alternative: in addition to their size...

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Detalles Bibliográficos
Autores principales: van der Put, Robert M. F., Spies, Arnoud, Metz, Bernard, Some, Daniel, Scherrers, Roger, Pieters, Roland, Danial, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453738/
https://www.ncbi.nlm.nih.gov/pubmed/36007249
http://dx.doi.org/10.1021/acs.analchem.2c01590