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RK-33, a small molecule inhibitor of host RNA helicase DDX3, suppresses multiple variants of SARS-CoV-2

SARS-CoV-2, the virus behind the deadly COVID-19 pandemic, continues to spread globally even as vaccine strategies are proving effective in preventing hospitalizations and deaths. However, evolving variants of the virus appear to be more transmissive and vaccine efficacy toward them is waning. As a...

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Detalles Bibliográficos
Autores principales: Vesuna, Farhad, Akhrymuk, Ivan, Smith, Amy, Winnard, Paul T., Lin, Shih-Chao, Panny, Lauren, Scharpf, Robert, Kehn-Hall, Kylene, Raman, Venu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453862/
https://www.ncbi.nlm.nih.gov/pubmed/36090095
http://dx.doi.org/10.3389/fmicb.2022.959577