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Cation-Exchangeable Pralidoxime Chloride@bio-MOF-1 as a Treatment for Nerve Agent Poisoning and Sulfur Mustard Skin Poisoning in Animals

[Image: see text] A 2-PAM@bio-MOF-1 composite was prepared by cationic exchange of counter N,N-dimethylammonium cations in the pores of the anionic, biocompatible metal–organic framework (bio-MOF-1) with pralidoxime chloride (2-PAM-Cl) by impregnation. In vitro drug release measurements revealed tha...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Liu, Jie, Liu, Lin, Zhou, Yunshan, Zhang, Lijuan, Zhong, Yuxu, Zhao, Dianfa, Wang, Yong’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453934/
https://www.ncbi.nlm.nih.gov/pubmed/36092617
http://dx.doi.org/10.1021/acsomega.2c01240