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METTL1 promotes neuroblastoma development through m(7)G tRNA modification and selective oncogenic gene translation

BACKGROUND: Neuroblastoma (NBL) is the most common extra-cranial solid tumour in childhood, with prognosis ranging from spontaneous remission to high risk for rapid and fatal progression. Despite existing therapy approaches, the 5-year event-free survival (EFS) for patients with advanced NBL remains...

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Detalles Bibliográficos
Autores principales: Huang, Ying, Ma, Jieyi, Yang, Cuiyun, Wei, Paijia, Yang, Minghui, Han, Hui, Chen, Hua Dong, Yue, Tianfang, Xiao, Shu, Chen, Xuanyu, Li, Zuoqing, Tang, Yanlai, Luo, Jiesi, Lin, Shuibin, Huang, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454133/
https://www.ncbi.nlm.nih.gov/pubmed/36071474
http://dx.doi.org/10.1186/s40364-022-00414-z