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Scalable, ultra-fast, and low-memory construction of compacted de Bruijn graphs with Cuttlefish 2
The de Bruijn graph is a key data structure in modern computational genomics, and construction of its compacted variant resides upstream of many genomic analyses. As the quantity of genomic data grows rapidly, this often forms a computational bottleneck. We present Cuttlefish 2, significantly advanc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454175/ https://www.ncbi.nlm.nih.gov/pubmed/36076275 http://dx.doi.org/10.1186/s13059-022-02743-6 |