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Low-dose spironolactone ameliorates adipose tissue inflammation and apoptosis in letrozole-induced PCOS rat model

BACKGROUND OF STUDY: Globally, many reproductive aged women are affected by polycystic ovarian syndrome (PCOS), which is a common endocrine and metabolic disorder that is linked with adipose dysfunction and chronic low-grade inflammation. Spironolactone (SPL), a mineralocorticoid receptor blocker ha...

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Detalles Bibliográficos
Autores principales: Areloegbe, Stephanie E., Peter, Mmenyene U., Oyeleke, Mosunmola B., Olaniyi, Kehinde S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454226/
https://www.ncbi.nlm.nih.gov/pubmed/36071485
http://dx.doi.org/10.1186/s12902-022-01143-y