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The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa

[Image: see text] The opportunistic pathogen Pseudomonas aeruginosa causes antibiotic-resistant, nosocomial infections in immuno-compromised individuals and is a high priority for antimicrobial development. Key to pathogenicity in P. aeruginosa are biofilm formation and virulence factor production....

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Detalles Bibliográficos
Autores principales: Taylor, Isabelle R., Jeffrey, Philip D., Moustafa, Dina A., Goldberg, Joanna B., Bassler, Bonnie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454246/
https://www.ncbi.nlm.nih.gov/pubmed/35985643
http://dx.doi.org/10.1021/acs.biochem.2c00334