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Reduced peroxisome proliferator-activated receptor-α and bile acid nuclear receptor NR1H4/FXR may affect the hepatic immune microenvironment of biliary atresia

BACKGROUND: Biliary atresia (BA) is a childhood liver disease characterized by fibrous obstruction and obstruction of the extrahepatic biliary system and is one of the most common and serious biliary disorders in infants. Significant inflammation and fibrosis of the liver and biliary tract are the m...

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Detalles Bibliográficos
Autores principales: Ma, Yingxuan, Lu, Li, Tan, Kezhe, Li, Zhi, Guo, Ting, Wu, Yibo, Wu, Wei, Zheng, Lulu, Fan, Feilong, Mo, Jiayu, Gong, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454303/
https://www.ncbi.nlm.nih.gov/pubmed/36090996
http://dx.doi.org/10.3389/fimmu.2022.875593