COL17A1 editing via homology-directed repair in junctional epidermolysis bullosa

BACKGROUND: Epidermolysis bullosa (EB), a severe genetic disorder characterized by blister formation in skin, is caused by mutations in genes encoding dermal-epidermal junction proteins that function to hold the skin layers together. CRISPR/Cas9-induced homology-directed repair (HDR) represents a pr...

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Detalles Bibliográficos
Autores principales: Petković, Igor, Bischof, Johannes, Kocher, Thomas, March, Oliver Patrick, Liemberger, Bernadette, Hainzl, Stefan, Strunk, Dirk, Raninger, Anna Maria, Binder, Heide-Marie, Reichelt, Julia, Guttmann-Gruber, Christina, Wally, Verena, Piñón Hofbauer, Josefina, Bauer, Johann Wolfgang, Koller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454317/
https://www.ncbi.nlm.nih.gov/pubmed/36091706
http://dx.doi.org/10.3389/fmed.2022.976604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454317/
https://www.ncbi.nlm.nih.gov/pubmed/36091706
http://dx.doi.org/10.3389/fmed.2022.976604

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