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Paving the Way to Solid Tumors: Challenges and Strategies for Adoptively Transferred Transgenic T Cells in the Tumor Microenvironment

SIMPLE SUMMARY: Adoptive transfer of T cells targeting tumors still remains mainly ineffective in solid entities. In this review we discuss challenges related to the tumor microenvironment (TME) and promising strategies to improve tumor control by engineering the TME or the transferred T cells thems...

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Detalles Bibliográficos
Autores principales: Füchsl, Franziska, Krackhardt, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454442/
https://www.ncbi.nlm.nih.gov/pubmed/36077730
http://dx.doi.org/10.3390/cancers14174192